منابع مشابه
Kinetic studies on [methionine sulphoxide] cytochrome c.
A cytochrome c haem ligand, methionine-80, was photo-oxidized to methionine sulphoxide and the subsequent changes in redox properties and ligand binding were monitored kinetically. Isoelectric focusing of the product showed the presence of a single oxidized species, capable of binding CO when reduced. The binding of CO to the reduced protein was followed in stopped-flow experiments, which revea...
متن کاملTumor uptake studies of S-adenosyl-L-[methyl-11C]methionine and L-[methyl-11C]methionine.
Tumor accumulation of S-adenosyl-L-[methyl-11C]methionine ([11C]SAM) was investigated in mice bearing mammary carcinoma (FM3A) and in rats bearing ascitic hepatoma (AH109A). After injection of [11C]SAM the blood clearance of 11C radioactivity was rapid. The 11C level was relatively high in both tumors. The uptake ratios of tumor to organ increased with time in several organs, especially in brai...
متن کاملInhibition of glutamine synthetase by methionine sulfoximine. Studies on methionine sulfoximine phosphate.
The irreversible inhibition of glutamine synthetase by methionine sulfoximine is associated with the tight binding to the enzyme of adenosine diphosphate and methionine sulfoximine phosphate; the latter compound can be cleaved nonenzymatically and also by phosphatases to equimolar amounts of methionine sulfoximine and inorganic phosphate. Methionine sulfoximine phosphate is oxidized by L-amino ...
متن کاملStudies on the Terminal Reaction in the Biosynthesis of Methionine.
It has been established from studies with Escherichia coli mutants (1,2) and animal liver (3,4) that 1\Is-methyltetrahydrofolic acid (5-CH3-folate-H4) transfers its methyl group to homocysteine to form methionine. The functions of the complex requirements for this reaction (reduced flavin (1,5), S-adenosylmethionine (AMe)l(4), and a cobalamin compound (6-8)) have not yet been fully elucidated. ...
متن کاملBioavailability comparison between herbal methionine and DL-methionine on growth performance and immunocompetence basis in broiler chickens
BACKGROUND:Herbal methionine can be compared relative toDl-methionine with evaluation of bioavailability of this source ofmethionine. OBJECTIVES: An experiment was carried out todetermine the relative bioefficacy of herbal methionine (H-Met)®relative to DL-methionine (DL-Met) on performance criteria andimmunocompetence of Met sources in male broilers. Atotal of 160male broilers were fed a Met-d...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1939
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)73438-8